DuoQuinol® is a unique combination of ubiquinol CoQ10 and geranylgeraniol (GG), developed and produced by American River Nutrition in the US. Ubiquinol is a key player in cellular energy production, while geranylgeraniol – a building block of CoQ10 – further supports mitochondrial and skeletal muscle health.
CoQ10 is produced naturally in the body and essential for everything from energy production to heart and brain health. But our ability to produce it declines with age or if we are taking certain medications such as statins. Additionally, if taken as a supplement, it can be hard for the body to absorb.
DuoQuinol® attempts to solve this issue.
It takes the ubiquinol form of Coq10 (biologically identical to the ubiquinol in your body) and combines it with GG (a little-known substance derived from the annatto plant that aids the body by naturally stimulating CoQ10 production). GG not only makes CoQ10 more bio-available by dissolving the CoQ10 to hep it reach the cells more effectively, it also acts as a natural building block to stimulate the body to make its own CoQ10, along with promoting muscle function and strength, bone health and other advantages.
Watch the short video below featuring Dr Barrie Tan, Chief Scientific Officer at American River Nutrition and creator of DuoQuinol® to learn how it provides crucial nutrients to help protect statin users from potential harmful side effects.
To see the full 25 minute interview click here.
One of the key reasons for developing DuoQuinol® was to help statin users.
Dr Tan says, "CoQ10 addresses only part of the equation of statin side effects. While CoQ10 supplementation raises endogenous levels of the nutrient and alleviates energy deficits, it does not remedy the muscle pain and weakness that some patients experience".
In fact, he sees the drop in CoQ10 levels when people take statin drugs as actually a biomarker for a drop in GG. And that's the reason for developing this product. By combining CoQ10 and GG in one capsule you can take a statin drug and theoretically you can protect your physiology from “collateral damage” of statin side effects.
DuoQuinol®’s unique absorption technology uses GG as a natural way of dissolving ubiquinol to increase its bioavailability.
American River Nutrition manufactures DuoQuinol® at their state-of-art 24,000 sq. ft. GMP facility in Hadley, Massachusetts, using a clean, purely physical extraction process.
Xtend-Quinol uses a patented blend of CoQ10 in the form of ubiquinol, and Geranylgeraniol (GG), manufactured by American River Nutrition. DuoQuinol®’s unique absorption technology utilizes GG as a natural solubilizer to increase bioavailability of the ubiquinol (the ubiquinone form of CoQ10 is less hydrophilic, and therefore has lower bioavailability).
The GG molecule is built into the same pathway the body uses to produce energy, and is an actual building block of CoQ10.
The unique combination of these two ingredients aims to boost your body’s natural levels of CoQ10 in two ways, with particular benefits for those on statin medications.
Ubiquinol is a naturally occurring nutrient in the body, with levels mostly concentrated in organs that use the most energy, including the heart, liver and kidneys. The powerful antioxidant helps to support the organs from damage and provides cellular energy.
Geranylgeraniol (GG) is made naturally in the body via the mevalonate pathway — the same biochemical pathway by which cholesterol, vitamin K2, steroid homones and CoQ10 are synthesized. It plays a critical role in tissue systems and metabolic processes throughout the body, including healthy mitochondrial function and energy production.
Similar to CoQ10, production of GG declines naturally during aging and is inhibited by use of certain pharmaceutical drugs, including statins. By replenishing natural levels, GG can protect from age-related physical decline (e.g. sarcopenia), support the body’s CoQ10 synthesis and energy production, and revoke skeletal muscle fatigue.
Studies have suggested that Ubiquinol supports healthy neurological and brain function.
Ubiquinol CoQ10 plays a key role in sperm cell energy production and motility.
Several studies on CoQ10 show that it supports heart health by helping with circulation, a healthy cholesterol profile and normal blood sugar levels.
Ubiquinol helps to manage free radical activity in the body by binding to them and allowing them to be safely eliminated from the body. This action allows CoQ10 to help defy the visible effects of aging.
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